Biochemistry
The Department of Biochemistry is located in the third floor of the faculty block. It comprises of one Professor and Head of the Department, one Associate Professor, two Senior Assistant Professors, four Tutors, two skilled lab technicians and one office assistant.
The Department of biochemistry is involved in teaching and training undergraduate students (MBBS, BSc Medical Lab Technicians, Diploma in Medical Lab Technicians)
We conduct 80 hours of lecture on biochemistry and molecular biology (theory), 150 hours of small group teaching, tutorials, integrated teaching including practical sessions, 20 hours of self-directed learning (SDL), 30 hours of early clinical exposure (ECE), 7 hours of AETCOM (Attitude, Ethics and Communication module), 5 hours of sports and extra-curricular activities) We also conduct formative assessment, summative assessment and term examinations.
FACILITIES AVAILABLE:
The Department is well equipped with research equipments such as high speed ultra centrifuge, spectrophotometers, protein electrophoresis unit, chromatography chamber, semi-auto analyser, incubator, pH meters. General facilities such as balance, microscope, water bath, colorimeter, spectroscope, laboratory fume hood, distilled water plant, refrigerator are also available.
MBBS students are encouraged to indulge in and apply for research activities like ICMR STS projects (Indian Council of Medical Research) every year.
Publications
| Sl.No | Faculty Name | Publication (Vancouver style) | Pubmed Indexed | Scopus | Embase | Index Copernicus |
|---|---|---|---|---|---|---|
| 1 | Dr. M. Manonmani | Manonmani M, Kuzhandai Velu V, Manimekalai K. A study of serum soluble CD40 ligand level & its correlation with serum CKMB & lipid profile in patients with acute coronary syndrome. Int J Clin Biochem Res. 2018;3(2):173-179 | No | No | Yes | No |
| Manonmani M, Manimekalai K. Study of serum Magnesium levels in Type 2 DM patients. J Diabetes Mellitus. 2018;8:20-26 | No | No | Yes | No | ||
| Manonmani M, Kavitha M. Association of serum lactate levels with CKMB and lactate dehydrogenase in patients with myocardial infarction. Int J Sci Res. 2020; DOI:10.36106/ija | No | No | Yes | No | ||
| Kavitha M, Manonmani M. Thyroid profile in children with nephritic syndrome. 2021; DOI:10.36106/ija | No | No | Yes | No | ||
| Manonmani M, Kavitha M, Vasanth S. A study of attitude of undergraduate MBBS students towards different teaching methods. Int J Pharm Clin Res. 2023;15(7):415-417 | No | No | Yes | No | ||
| Manonmani M, Kavitha M. Growth parameters & growth hormone levels in children with nephritic syndrome. Int J Pharm Clin Res. 2023;15(7):432-434 | - | - | - | - | ||
| 2 | Dr. Shanmuga Priya, MD (Bio) | Association of endothelial lipase genotype with serum HDL, cholesterol and its sub-fractions in response to exercise training | - | - | - | - |
| Molecular basis of retinoblastoma and application of the basis for improving quality of clinical management in proband | - | - | - | - | ||
| The Gln-Arg192 Polymorphism of Human Paraoxonase 1 Gene And The Associated Phenotype Variation Is Associated With Coronary Artery Disease | - | - | - | - | ||
| TCF7L2 gene variant rs7903146 affects the risk of Type 2 Diabetes by modulating incretin secretion | - | - | - | - | ||
| Evaluation of pKa as a cause of discordance between calculated and measured bicarbonate in arterial and venous blood | - | - | - | - | ||
| Comparison of sodium fluoride and serum separator tubes for blood glucose estimation - what’s the best option? | - | - | - | - | ||
| 3 | Dr. Romy W. Marshnil, MD (Bio) | Romy W. Marshnil, Mythili C. Study of serum magnesium levels and its correlation with glycated hemoglobin levels in Type 2 Diabetes Mellitus. IOSR JDMS. 2018;17(6):22-27 | - | - | - | yes |
| Romy W. Marshnil, Mythili C. Correlation of serum calcium levels with glycated hemoglobin in Type 2 Diabetes Mellitus patients - a comparative study. IJSR. 2018;7(8):04-06 | Yes | - | - | Yes | ||
| Romy W. Marshnil, Aaron Vetha Jose J. Study on correlation between glycated hemoglobin and serum lipid profile in Type 2 Diabetes Mellitus. MedPulse Int J Biochem. 2020;13(1):04-08 | - | - | - | yes | ||
| 4 | Dr. Michael Rajam Geetha, MD (Bio) | S. Michael Rajam Geetha, V.G. Karpaghavalli, J. Siva Somana. Correlation of serum leptin levels with disease activity in rheumatoid arthritis patients. Scholars J Appl Med Sci. 2017;5(8E):3309-3312 | - | - | - | yes |
| S. Michael Rajam Geetha, Siva Somana, V.G. Karpagavalli. The impact of obesity on the severity of rheumatoid arthritis. Int J Sci Res. 2018;7(1):55-56 | - | - | - | yes | ||
| M. Divya, K. Chandramouleeswari, S. Michael Rajam Geetha. Vitamin D deficiency and its independent role in renal damage in diabetes mellitus. Res J Pharm Biol Chem Sci. 2021;12(3):129-132 | - | - | yes | - | ||
| V. Rajasekar, S. Michael Rajam Geetha, Sunitha Kandasamy, A. Abiselvi. Prevalence of self-medication practices among pregnant mothers in urban Thoothukudi. Res J Pharm Biol Chem Sci. 2022;13(2):138-144 | - | - | yes | - | ||
| Karthiga Murugan, Velmurugan Anbuananthan, S. Michael Rajam Geetha, Vijayalakshmi Masilamani. A hospital-based case control study on serum lipid profile in active rheumatoid arthritis patients. Res J Pharm Biol Chem Sci. 2022;13(4):121-125 | - | - | yes | - | ||
| 4 | Dr. Sivasomana, MD (Bio) | Siva Somana J, Mahalakshmi R, Vijayalakshmi M. Comparison of measurement of direct LDL-C vs calculated LDL-C. Stanley Med J. 2016;3(4):11-14 | - | - | - | yes |
| Siva Somana J, Mahalakshmi R, Vijayalakshmi M. Prevalence of subclinical hypothyroidism in patients with chronic kidney disease. Stanley Med J. 2017;4(2):14-18 | - | - | - | yes | ||
| S. Michael Rajam Geetha, V.G. Karpaghavalli, J. Siva Somana. Correlation of serum leptin levels with disease activity in rheumatoid arthritis patients. Scholars J Appl Med Sci. 2017;5(8E):3309-3312 | - | - | - | yes | ||
| S. Michael Rajam Geetha, Siva Somana, V.G. Karpagavalli. Impact of obesity on severity of rheumatoid arthritis. Int J Sci Res. 2018;7(1):55-56 | - | - | - | yes | ||
| J Siva Somana*, T Uma, K Anuja, V Gomathi. Evaluation of AMH levels and correlation with LH/FSH ratio in women of reproductive age group. Res J Pharm Biol Chem Sci. 2021;12(4):140-145 | DOAJ | - | - | - | ||
| T Uma, J Siva Somana*, R Kalaivani, V Gomathi. Lipoprotein (a) cholesterol quantification and correlation with LDL cholesterol and ratios in diagnostic assessment of CVD. Res J Pharm Biol Chem Sci. 2021;12(6):59-63 | DOAJ | - | - | - | ||
| 5 | Dr. M. Archana, MD (Bio) | Mony A, Batmanabane M. Effect of obestatin on body weight, serum glucose and insulin levels in albino rats. Eur J Anat. 2015;17(2):59-62 | Yes | - | - | Yes |
| Varghese R, Rajappa M, Chandrashekar L, Kattimani S, Archana M, Munisamy M, Revathy G, Thappa DM. Association among stress, hypocortisolism, systemic inflammation, and disease severity in chronic urticaria. Ann Allergy Asthma Immunol. 2016;116(4):344-348 | Yes | - | - | Yes | ||
| Anisha Sharma, Binita Goswami, Archana M, Medha Rajappa. Comparison of co-peptin, H-FABP, Troponin-I and CK-MB assays as diagnostic biomarkers in patients with myocardial infarction. Int J Sci Res. 2016;5:1040-1043 | Yes | - | - | Yes | ||
| Gade VKV, Mony Archana, et al. Investigation of vitamin D status in alopecia areata. Clin Exp Med. 2018;17:577-584 | Yes | Yes | - | - | ||
| Archana Mony et al. Effect of vitamin D supplementation on clinical outcome in vitamin D-deficient chronic urticaria. Clin Chim Acta. 2020;504:1-6 | Yes | Yes | - | - | ||
| 6 | Dr. Nageshwari A | Nageshwari A, Geetha K, Bhuvaneswari R. Study of serum calcium, magnesium, phosphorus, and lipid profile in pre-menopausal women. Res J Pharm Biol Chem Sci. 2024;15(2):1-3 | No | No | Embase (Elsevier) | No |
| Shobana B, Nageshwari A, Menaka Shanthi K. Utility of serum cholinesterase, LDH, AST/ALT ratio, albumin/globulin ratio in differentiating alcoholic liver disease from NASH. RJPBCS. 2024;15(4) | No | No | Embase (Elsevier) | No | ||
| Nageshwari A, Sudha Prasanna B, Geetha K. Serum aminotransferase levels in chronic kidney disease. RJPBCS. 2023;14(3):232 | No | No | Embase (Elsevier) | No | ||
| B. Sudha Prasanna, R. Gayathri, A. Nageshwari. Covid positive anaemic pregnant women at tertiary care centre. RJPBCS. 2023;14(3):237 | No | No | Embase (Elsevier) | No | ||
| Kavitha G, Nageshwari A. Prevalence of metabolic syndrome in euthyroid patients. Int Arch Integr Med. 2019;6(6):36-40 | No | No | No | Index copernicus | ||
| Nageshwari A, Kavitha G. Influence of ferritin on thyroid hormones in second trimester antenatal cases. IAIM. 2019;6(1):30-34 | No | No | No | Index copernicus | ||
| Kavitha G, Nageshwari A. FGF23 among chronic renal failure patients. Int Arch Integr Med. 2018;5(6):1-7 | No | No | No | Index copernicus | ||
| 7 | Dr. D. Sobana | Sobana D, Mahima Alicia M, Nagendran R. Study of high sensitivity C-reactive protein levels in subclinical hypothyroid patients. Int J Sci Res. | No | No | No | No |
| Sobana D, Saravanan S, Nagendran R. Study of inflammatory markers in Covid-19 patients. Int J Sci Res. | No | No | No | No | ||
| Mahima Alicia M, Sobana D, Nagendran R. Association between serum ferritin and hypertension in patients attending tertiary care hospital. Int J Sci Res. | No | No | No | No |
CME Programs conducted in the department.
ICMR Projects in Biochemistry
-
Dr. Prasanna Kumar (2019-2020)
Project: ‘HDL levels in diabetes mellitus patients’
Guide: Dr. Shanmugapriya C -
Dr. Sugavarshini Palaniyappan
Project: Role of PGE2, Decoy receptor 3, Lipoxin as apoptotic markers in predicting diagnosis and prognosis of active Tuberculosis in South Indian population
Guide: Dr. Romy W. Marshnil, MD (Bio) -
Dr. S. Kishore (2023 batch)
Project: Association between hyperuricemia and coronary kidney disease - prospective observational study
Guide: Dr. Nageshwari A
Awards / Medals & Research Activities
Inter Department Quiz
Elsevier Basic Sciences Olympiad 2018 - Biochemistry Quiz Winners
| 1st Prize | Vijay Harinath.S |
| 2nd Prize | Venkadesh.V |
| 3rd Prize | Ramani Kumar.K.U and Sharandeep.P |
Intra Department Quiz
Intradepartmental Quiz 2022 - Biochemistry Quiz Winners
| 1st Prize | Umamageswari |
| 2nd Prize | Safin Solomon |
| 3rd Prize | Iswarya Sakthi |
Research Activities: Ongoing Projects (to be published)
-
Project: Serum urea and Serum creatinine in patients with type-2 Diabetes Mellitus and their prognostic role as effective renal markers in type-2 diabetes.
Authors: Romy W. Marshnil¹, Archana Mony², Ganesh G³, *Aaron Vetha Jose J. -
Project: The role of glycemic status in onset of microalbuminuria in patients with Diabetes Mellitus.
Authors: Romy W. Marshnil¹, Archana Mony², Ganesh G³, *Aaron Vetha Jose J. -
Project: Body mass index and its effect on microalbumin, glycated haemoglobin and serum total cholesterol levels in Diabetes.
Authors: Romy W. Marshnil¹, Archana Mony², Ganesh G³, *Aaron Vetha Jose J.
Other facilities available are:
A spacious well equipped laboratory for MBBS students with a capacity of 75 students at a time. There is also a Biochemistry laboratory for students undergoing Medical Lab Technician course with a capacity of 30 students at a time.
Updated departmental library with 183 books, 20 National & International Journals.
Two demo rooms for undergraduates with a seating capacity of 75 members each.
Air conditioned research laboratory.
24 hours Central Lab of Biochemistry attached to Thoothukudi Govt. Medical College Hospital. The following tests are done
| Lab Tests | Lipid Profile |
|---|---|
| Glucose Random | Total Cholesterol |
| Glucose PPBS | TGL |
| Glucose Fasting | HDL |
| LDL | |
| Renal Function Test | |
| VLDL | |
| Urea | |
| Creatinine | Liver Function Test |
| Bilirubin Total | |
| Serum Electrolytes | |
| Direct | Indirect |
| Sodium | Total Protein |
| Potassium | Albumin |
| Chloride | Globulin |
| calcium | A/G Ratio |
| Thyroid Profile | |
| AST/SGOT | |
| Free T3 | ALT/SGPT |
| Free T4 | Alkaline Phosphatase |
| TSH | ABG Analysis |
| Inflammatory Markers | |
| IL -6 | pH, pCo2, po2, Hco3- |
| CRP | |
| FERRITIN | URINE TEST |
| D-DIMER | Urine routine, PCR, ACR, MICROALBUMIN |
Distinctions and Honours in University Exams
MBBS - 2023 Batch
| S.No | Name of the Student | Honors / Distinction |
|---|---|---|
| 1 | Sankeerthana | Honor in Biochemistry |
| 2 | Abisri | Honor in Biochemistry |
| 3 | Sankar | Honor in Biochemistry |
| 4 | Rajarajan | Distinction in Biochemistry |
| 5 | Pradeep | Distinction in Biochemistry |
| 6 | Dharmaraj | Distinction in Biochemistry |
| 7 | Rithiska | Distinction in Biochemistry |
| 8 | Minu | Distinction in Biochemistry |
| 9 | Seethalakshmi | Distinction in Biochemistry |
MBBS - 2022 Batch
| S.No | Name of the Student | Honors / Distinction |
|---|---|---|
| 1 | Anu Vidhyaa | Distinction in Biochemistry |
| 2 | Anusree G | Distinction in Biochemistry |
| 3 | Babhi Bousteena B | Distinction in Biochemistry |
| 4 | Dharshini.C | Distinction in Biochemistry |
| 5 | Jeevadharshani S | Distinction in Biochemistry |
| 6 | Keerthana.R | Distinction in Biochemistry |
| 7 | Kishore Kumar K.S | Distinction in Biochemistry |
| 8 | Lakshmi Praveen M | Distinction in Biochemistry |
| 9 | Nandhini A | Distinction in Biochemistry |
| 10 | Priyadharshini D | Distinction in Biochemistry |
| 11 | Rohith T | Distinction in Biochemistry |
| 12 | Shanmathi.R | Distinction in Biochemistry |
| 13 | Shanmugapriya M | Distinction in Biochemistry |
| 14 | Subikshaa U | Distinction in Biochemistry |
| 15 | Sunil Larisha R | Distinction in Biochemistry |
| 16 | Tharunika K.J | Distinction in Biochemistry |
| 17 | Vignesh D | Distinction in Biochemistry |
MBBS - 2021 Batch
| S.No | Name of the Student | Honors / Distinction |
|---|---|---|
| 1 | Sankeerthana | Honor in Biochemistry |
| 2 | Abisri | Honor in Biochemistry |
| 3 | Sankar | Honor in Biochemistry |
| 4 | Rajarajan | Distinction in Biochemistry |
| 5 | Pradeep | Distinction in Biochemistry |
| 6 | Dharmaraj | Distinction in Biochemistry |
| 7 | Rithiska | Distinction in Biochemistry |
| 8 | Minu | Distinction in Biochemistry |
| 9 | Seethalakshmi | Distinction in Biochemistry |
MBBS - 2019 Batch
| S.No | Name of the Student | Honors / Distinction |
|---|---|---|
| 1 | Howsalya K | Honor in Biochemistry |
| 2 | Prasanna Kumar | Honor in Biochemistry |
| 3 | Jaaiza | Honor in Biochemistry |
| 4 | Poorna Sambhavi | Honor in Biochemistry |
| 5 | Natarajan | Honor in Biochemistry |
| 6 | Dharshan | Honor in Biochemistry |
| 7 | Mohammad Riaz | Honor in Biochemistry |
| 8 | Leela | Honor in Biochemistry |
| 9 | Gopi Krishnan | Honor in Biochemistry |
| 10 | Anandapadmanabhan | Honor in Biochemistry |
| 11 | Gunanidhi | Honor in Biochemistry |
| 12 | Haritha | Distinction in Biochemistry |
| 13 | Priyadarshini R | Distinction in Biochemistry |
| 14 | Juliyana Rani | Distinction in Biochemistry |
| 15 | Saranya | Distinction in Biochemistry |
| 16 | Saivignesh | Distinction in Biochemistry |
| 17 | Thilak | Distinction in Biochemistry |
| 18 | Keerthana P | Distinction in Biochemistry |
| 19 | Shrinithi | Distinction in Biochemistry |
| 20 | Sreeja | Distinction in Biochemistry |
| 21 | Cicily Chacko | Distinction in Biochemistry |
| 22 | Kavitha | Distinction in Biochemistry |
| 23 | Jemima | Distinction in Biochemistry |
| 24 | Srivatsa | Distinction in Biochemistry |
| 25 | Vinayak Prasad | Distinction in Biochemistry |
| 26 | Sneka SD | Distinction in Biochemistry |
| 27 | Sibi Siddarth | Distinction in Biochemistry |
| 28 | Vigasini | Distinction in Biochemistry |
| 29 | Feras | Distinction in Biochemistry |
| 30 | Bharathi S | Distinction in Biochemistry |
| 31 | Dhanasekar | Distinction in Biochemistry |
| 32 | Sonia John | Distinction in Biochemistry |
| 33 | Mei Gayathri | Distinction in Biochemistry |
| 34 | Sujitha | Distinction in Biochemistry |
| 35 | Amitha Babu | Distinction in Biochemistry |
| 36 | Jayashree J | Distinction in Biochemistry |
| 37 | Fathima Siddiqua | Distinction in Biochemistry |
| 38 | Thangaslelvam | Distinction in Biochemistry |
| 39 | Akash | Distinction in Biochemistry |
| 40 | Ilakiya P I | Distinction in Biochemistry |